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CIHR Skin Research Training Centre
Fengtao Shi

 

Fengtao Shi (Postdoctoral Fellow)

Supervisor: Dr. Kevin McElwee; 

Term: 2013-03-01~Present

Project title: Identifying adult mesenchymal stem cells in hair follicles and defining their role in hair loss

                                                                                                                                                     
                                                               

I was educated at Sun Yat-Sen University, China (B.Sc and M.Sc) and then did my PhD at University of British Columbia with Dr. Peter CK Leung, investigating the mechanisms of growth differentiation factor 9 (GDF9), which is a member of TGFβ superfamily and mainly secreted by oocyte, on activin A-stimulated inhibin B production and activin A-reduced progesterone production in human granulosa-lutein cells from IVF patients. After that, I received two years of Postdoctoral training at Baylor College of Medicine, United States and my main projects were: 1) To examine the role of O-GlcNAc transferase (Ogt) at the gene repression functions of Ten-Eleven Translocation 1(Tet1) protein in mouse embryonic stem cells; 2) To explore the roles of long non-coding RNAs (lncRNAs) in regulating pluripotency and differentiation in mouse embryonic stem cells. I then returned to Canada recently as a Postdoctoral Research Fellow at Dr. Kevin McElwee’s hair research laboratory. My work is to identify adult mesenchymal stem cells (MSCs) in hair follicles and define their role in hair loss. We expect this research will improve our understanding of disease development and could enable new treatment regimens targeting hair follicle MSCs.


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