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CIHR Skin Research Training Centre
Core Mentors: Dr. Harvey Lui
Harvey Lui, MD, FRCPC
Professor and Head/Chairman, Department of Dermatology and Skin Science, University of British Columbia 
Director, the CIHR Skin Research Training Centre and the VGH Photomedicine Institute
Medical Director, The Skin Care Centre, the Lions Laser Skin Centre, and the Psoriasis & Phototherapy Clinic
Secretary-General, 23rd World Congress of Dermatology, Vancouver 2015

835 West 10th Ave 
Vancouver, BC V5Z 4E8 
Tel: 604 875-4747
Fax: 604 873-9919
Website: http://www.skincarecentre.ca/about_us/doctors/harvey_lui.htm  
Email: harvey.lui@ubc.ca
                                                                                                                                     

Education

1979-1983 BSc, UBC
1986 MD, UBC
1991-1992 Clinical Fellow, the Massachusetts General Hospital, Harvard Medical School

Awards and honors

2001 Killam Prize, University of British Columbia            

Research interest and academic activities

Dr. Lui has been the principal investigator in over 35 research projects, has published over 104 peer-reviewed papers, 11 book chapters, and is the co-inventor of 6 patents for dermatology. His clinical and research interests include lasers, photomedicine, psoriasis, vitiligo, and dermatologic education.
Dr. Lui was the founding Web Editor for the Archives of Dermatology and is currently on the editorial board for three journals. He is an active member of the American Academy of Dermatology, American Dermatological Association, European Academy of Dermatology and Venereology, Photomedicine Society, International Photodynamic Association, and Canadian Dermatology Association.
In 2005, Dr. Lui was the President of the Canadian Dermatology Association. Prof. Lui was recently elected in 2011 to serve as an International Board Member to the International League of Dermatologic Societies.
To date, Prof. Lui has given invited presentations in photomedicine and dermatology education in 26 different countries. He has also served on the organizing committees of several international conferences including the World Congress of Photodynamic Medicine, Sixth World Congress on Melanoma, Fifth International Congress on Hair Research, Pan-American Pigmentation & Melanoma Research Congress, and the Canadian Dermatology Association. He is regularly invited to be on the program of each AAD, and was a member of the AAD’s Scientific Assembly Committee in 2006. Dr. Lui has participated as a speaker or chairman at every World Congress of Dermatology since the last North American WCD in New York in 1992, and will be the Secretary-General for the 23rd World Congress of Dermatology in 2015.  

Selected recent publications

  1. Short MA. Lam S. McWilliams A. Zhao J. LUI H. Zeng H. Development and preliminary results of an endoscopic Raman probe for potential in vivo diagnosis of lung cancers. Optics Letters 2008; 33:711-3.
  2. Zeng H, Zhao J, Short M, Mclean DI, Lam S, McWilliams A, LUI H. Raman spectroscopy for in vivo tissue analysis and diagnosis, from instrument development to clinical applications. J Innovation in Optical Health Sciences 2008; 1:95–106.
  3. Tchvialeva L, Lee TK, Markhvida I, McLean DI, LUI H, Zeng H. Using a zone model to incorporate the influence of geometry on polychromatic speckle contrast. Optical Engineering 2008; 47(7):074201.
  4. Zhao J, LUI H, McLean DI, Zeng H. Integrated real-time Raman system for clinical in vivo skin analysis. Skin Res Technol 2008; 14:484-492.Taylor S, Grimes P, Lim J, Im S, LUI H. Post-inflammatory hyperpigmentation: A review. J Cutan Med Surg 2009; 13:183-91.
  5. Cluff, GM, Short, MA, LUI, H, McLean, DI, Zeng, H, Korbelik, M, Chen, MX: Comparison of connective tissue invaded by Lewis lung carcinoma to healthy connective tissue by means of micro-Raman spectroscopy. J Raman Spectrosc 2009; 40:1087-1090.
  6. Ortonne JP, Arellano I, Berneburg M, Cestari T, Chan H , Grimes P, Hexsel D, Im S, Lim J, Lui H, Pandya A, Picardo M, Rendon M, Taylor S, Van Der Veen JPW, Westerhof W. A global survey of the role of ultraviolet radiation and hormonal influences in the development of melasma. J Eur Acad Dermato Venereol 2009; 23:1254-1262.
  7. Han X, LUI H, McLean DI, Zeng H. Near-infrared autofluorescence imaging of cutaneious melanis and human kin in vivo. J Biomed Optics 2009; 14(2): 024017.
  8. Ortiz-Policarpio B, H. Lui H. Methyl aminolevulinate-PDT for actinic keratoses and superficial nonmelanoma skin cancers. Skin Therapy Letter 2009; 14(6):1-3.
  9. Taylor S, Grimes P, Lim J, Im S, Lui H. Postinflammatory hyperpigmentation. J Cutan Med Surg 2009; 13:183–91.
  10. Humphrey S, Martinka M, LUI H. Cutaneous protothecosis following a tape-stripping injury. J Cutan Med Surg 2009; 13, No 5 (September/October): pp 273–275
  11. Chen J, Lee A, Zhao J, Wang H, LUI H. McLean DI, Zeng H. Spectroscopic characterization and microscopic imaging of extracted and in situ cutaneous collagen and elastic tissue components under two-photon excitation. Skin Res Technol 2009; 15:418-426.
  12. Bissonnette R, Searles G, Landells I, Shear NH, Papp K, LUI H et al. Article 2: Demographics. AWARE Article Series, Study Methodology and Baseline Characteristics. J Cutan Med Surg 2009; 13 (Suppl 3): S113-121.
  13. Landells I, Searles G, Bissonnette R, Shear NH, Vender R, LUI H. Article 3: Outcomes. AWARE Article Series. Efficacy Outcomes in Patients Using Alefacept. J Cutan Med Surg 2009; 13 (Suppl 3): S122-S130.
  14. Searles G, Bissonnette R, Landells I, Shear NH, Papp K, LUI H. Article 4: Combination Therapy. AWARE Article Series. Patterns of combination therapy with Alefacept for the treatment of psoriasis in Canada. J Cutan Med Surg 2009; 13 (Suppl 3): S131-S138.
  15. Huang N, Wang H, Zhao J, LUI H, Korbelik M, Zeng H. Single-wall carbon nanotubes assisted photothermal cancer therapy – Animal study with a murine model of squamous cell carcinoma. Laser Surg Med 2010; 42:638–648.
  16. Tan J, Stacey D, Fung K, Barankin B, Bissonnette R, Gulliver W, LUI H et al. Treatment decision needs of psoriasis patients: A cross-sectional survey. J Cutan Med Surg 2010; 14(5):233-239.
  17. Tchvialeva L, Markhvida I, Zeng H, McLean DI, LUI L, Lee TK. Surface roughness measurement by speckle contrast under the illumination of light with arbitrary spectral profile. Optics and Lasers in Engineering 2010; 48:774-778.
  18. Aubert J Reiniche P, Fogel P, Poulin Y, LUI H, Lynde C, Shapiro J et al. Gene expression profiling of plucked anagen hairs of psoriatic scalp skin: Clobetasol propionate shampoo 0.05% normalizes psoriasis disease markers. J Eur Acad Dermatol 2010; 24:1304-11.
  19. Wang, S, Zhao J, LUI H, He Q, Zeng H. A modular near infrared Raman microspectroscopy system for biological tissue analysis. Spectrosc-Int J 2010; 24:577-583.
  20. Wang H, Huang N, Zhao J, LUI H, Korbelik M, Zeng H. Depth-resolved in vivo micro-Raman spectroscopy of a murine skin tumor model reveals cancer-specific spectral biomarkers. J Raman Spectrosc 2011; 42:160-166.
  21. Kirshen C, Shoimer I, Wismer J, DesGroseilliers JP, LUI H. Teaching dermatology to Canadian undergraduate medical students. J Cutan Med Surg 2011; 15:150-156.
  22. Wighton P, Lee TK, LUI H, McLean D, Atkins MS. Chromatic aberration correction: An enhancement to the calibration of low-cost digital dermoscopes. Skin Res Technol 2011; 17:339-347.
  23. Lee, AMD, Wang, H, Yu, Y, Tang S, Zhao J, LUI H, McLean DI, Zeng H. In vivo video rate multiphoton microscopy imaging of human skin. Optics Letters 2011; 36:2865-2867.
  24. Wang S, Zhao J, LUI H, He Q, Zeng H: Monte Carlo simulation of near infrared autofluorescence measurements of in vivo skin. J Photochem Photobiol B: Biol 2011; 105:183-189.
  25. Huang N, Short M, Zhao J, Wang H, LUI H, Korbelik M, Zeng H. Full range characterization of the Raman spectra of organs in a murine model. Optics Express 2011; 19:22892-22909.
  26. Monselise A, Shapiro J, Lui H. Inner canthus hypertrichosis: a side effect of prostaglandin analogue treatment for glaucoma. J Cutan Med Surg 2011; 15:298-9.
  27. Wighton P, Lee TK, Mori G, Lui H, McLean DI, Atkins MS. Conditional random fields and supervised learning in automated skin lesion diagnosis. Int J Biomed Imaging. 2011; 846312.
  28. Wighton P, Lee TK, LUI H, McLean DI, Atkins MS. Generalizing common tasks in automated skin lesion diagnosis. IEEE Transactions on Information Technology in Biomedicine 2011; 15:622-629.
  29. Zandi S, Kalia S, LUI H. UVA1 phototherapy: a concise and practical review. Skin Therapy Letter 2012; 17:1-4.
  30. Wang H, Zhao J, Lee AMD, LUI H, Zeng H: Improving skin raman spectral quality by fluorescence photobleaching. Photodiagnosis Photodynamic Ther 2012; (accepted Feb 2012)
  31. Wang H, Tsai TH, Zhao J, Lee AMD, Lo BKK, Yu M, LUI H, McLean DI, Zeng H: Differentiation of HaCaT cell and melanocyte from their malignant counterparts using micro-Raman spectroscopy guided by confocal imaging. Photodermatol Photoimmunol Photomed 2012; (accepted March 2012)
  32. LUI H, Zhao J, McLean D, Zeng H. Real-time Raman spectroscopy for in vivo skin cancer diagnosis. Cancer Res 2012; (accepted Mar 2012).
  33. Wang S, Zhao J, LUI H, He Q, Zeng H. In vivo near-infrared autofluorescence imaging of pigmented skin lesions: methods, technical improvements and preliminary clinical results. Skin Res Technol 2012 (accepted April 2012).

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